part of part of develops_from has potential to develop into epithelium embryo ectoderm internal ear ear vesicle AAO:0011080 BTO:0002661 EHDAA2:0001342 EMAPA:16669 Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. Kimmel et al, 1995. (Also see Anatomical Atlas entry for ear by T. Whitfield.)[TAO] FMA:302920 OV One of the paired sacs of invaginated ectoderm that develop into the membranous labyrinth of the internal ear. [Biology_online][VHOG] TAO:0000051 The inner ear develops embryonically in all vertebrates as an invagination of the ectodermal otic placode to form an otic vesicle.[well established][VHOG] The saccular invagination of ectoderm from which the vertebrate inner ear develops[BTO]. Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells[ZFA]. epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP] UBERON:0003051 UBERON:0004373 UMLS:C1518678 VHOG:0001148 XAO:0000006 ZFA:0000051 acoustic vesicle auditory vesicle otic vesicle otocyst uberon embryonic tissue otic pit presumptive structure structure with developmental contribution from neural crest ecto-epithelium