developmentally_induced_by immediate transformation of notochord neural plate presumptive central nervous system RETIRED_EHDAA2:0001252 EMAPA:35593 AAO:0011072 UMLS:C0920623 ZFA:0000132 TAO:0000132 A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA] VHOG:0000068 DMBA:15565 lamina neuralis EHDAA:902 (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] EHDAA:346 The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] XAO:0000249 FMA:293879 BTO:0001765 DHBA:10153 uberon UBERON:0003075 embryonic tissue presumptive neural plate ecto-epithelium future central nervous system