is evidence of
This represents a relation between two adverse events AE1 and AE2. However, AE1 may be an evidence of another adverse event AE3, and a dfferent adverse event AE4 may also be an evidence of the same AE2.
AE1 is_evidence_of AE2 if and only if: given an adverse event instance ae1 that instantiates class AE1 (e.g., electrocardiogram qt prolonged AE) and another adverse event instance ae2 that instantiates class AE2 (e.g., arrhythmia AE), both ae1 and ae2 are adverse events that are clinically observed after a medical intervention (at time t0) on the same patient. The presence of ae1 is supported by priori knowledge of medicine to imply the presence of ae2 with some probability P (P is NOT always 1, thus transitivity does not apply to is_evidence_of relation. AE1 is_evidence_of AE2 and AE2 is_evidence_of AE3 DOES NOT imply AE1 is_evidence_of AE3). The instance ae1 and ae2 are observed or detected at time t1 and t2, respectively. The biological onset time for ae1 or ae2 may occur before t1 or t2. The t1 and t2 can be the same time point or different time points.
SS, YH, YL
An electrocardiogram qt prolonged AE is_evidence_of arrhythmia AE; arrhythmia AE is_evidence_of cardiomyopathy AE; fever AE is_evidence_of inflammation AE; fever AE is_evidence_of viral infection AE; plural effusion AE is_evidence_of cardiac disorder AE.