part of
part of
develops_from
contributes to morphology of
composed primarily of
islet of Langerhans
endocrine pancreas
BTO:0000650
CALOHA:TS-1302
EFO:0002542
EMAPA:35305
EV:0100129
FMA:16018
In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]
MA:0001582
TAO:0001260
The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]
The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.
The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]
UBERON:0000016
VHOG:0000049
ZFA:0001260
create a separate class for distributed pancreas, eg cyclostomes?
endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys
endocrine pancreas
endocrine part of pancreas
islets of Langerhans part of pancreas
pars endocrina pancreatis
uberon
compound organ component
endocrine system
pancreas
dorsal pancreatic bud
endoderm-derived structure