part of
part of
develops_from
pancreatic epithelial bud
ventral pancreatic bud
AAO:0011111
EFO:0003464
EHDAA2:0001389
EMAPA:17256
In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]
TAO:0001369
The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP]
UBERON:0003924
VHOG:0001429
XAO:0001103
ZFA:0001369
anterior pancreatic anlage
anterior pancreatic bud
pancreas primordium ventral bud
pancreas ventral primordium duct bud
pancreatic bud that gives rise to the major pancreatic duct.
the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468]. TODO - add this relationship.
uberon
ventral pancreas anlage
ventral pancreatic anlage
hepatic diverticulum
pancreas ventral primordium