has role 1-methylnicotinamide A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent. nicotinamide pyridinium ion anti-inflammatory agent mouse metabolite Saccharomyces cerevisiae metabolite plant metabolite human urinary metabolite algal metabolite