has role has functional parent nicotinic acid nicotinamide A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. geroprotector vitamin B3 antioxidant cofactor pyridinecarboxamide pyridine alkaloid EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor neuroprotective agent anti-inflammatory agent Sir2 inhibitor mouse metabolite Saccharomyces cerevisiae metabolite Escherichia coli metabolite human urinary metabolite