has role hexahydronaphthalenes polyketide mevastatin A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from <em>Penicillium citrinum</em> and from <em>Penicillium brevicompactum</em>, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. antifungal agent apoptosis inducer 2-pyranones Penicillium metabolite EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor statin (naturally occurring)