has role carboxamidine dicarboxylic acid monoamide azetidines melagatran A member of the class of azetidines that is (2<i>S</i>)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2<i>R</i>)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. anticoagulant secondary amino compound serine protease inhibitor EC 3.4.21.5 (thrombin) inhibitor non-proteinogenic alpha-amino acid