sequence data input gene sequence start site Emma Griffiths input gene sequence start site Emma Griffiths query gene start site The position of the first nucleotide in a gene sequence being analyzed (input gene sequence). When a new genome is sequenced, the start sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The first nucelotide of a gene sequence being analyzed is the input gene sequence start site. input gene start metadata complete