Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions A group of renal cell carcinomas characterized by the presence of different translocations involving the chromosome Xp11.2. These translocations result in the creation of gene fusions involving the TFE3 gene. Patients are usually children and young adults. Morphologically, the malignant epithelial cells form papillary patterns. Renal Cell Cancer Associated with Xp11.2 Translocations/TFE3 Gene Fusions Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions TFE3-Rearranged Renal Cell Carcinoma Xp11.2 Translocation-Related Renal Cell Carcinoma tRCC