skin AE acanthosis nigricans AE 黑棘皮病 WEB: http://en.wikipedia.org/wiki/Acanthosis_nigricans Acanthosis nigricans AE is a skin AE that is a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas. JX, LW, YH MedDRA: 10000350