Epilepsy, Generalized [Disease/Finding] Epilepsy, Tonic-Clonic [Disease/Finding] Epilepsy, Grand Mal N0000001129 Tonic-Clonic Seizure Disorder Major Motor Seizure Disorder Epilepsy, Tonic-Clonic 1022827 Seizure Disorder, Grand Mal Tonic-Clonic Convulsion Disorder Epilepsy, Major Tonic-Clonic Convulsion Syndrome C0014549 A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329) M0007573 Tonic-Clonic Seizure Syndrome 352818000 Tonic Clonic Convulsions D004830 Seizure Disorder, Tonic Clonic Convulsions, Grand Mal Grand Mal Seizure Disorder Epilepsy, Tonic-Clonic C2436 Seizure Disorder, Major Motor