Glomerulonephritis [Disease/Finding] Glomerulosclerosis, Focal Segmental [Disease/Finding] Focal Segmental Glomerulosclerosis Glomerulosclerosis, Focal C0017668 D005923 Glomerulosclerosis, Focal Segmental Glomerulonephritis, Focal Sclerosing M0009302 N0000001353 Glomerulosclerosis, Focal Segmental 25821008 C2884 1026699 A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.