Multiple Sclerosis [Disease/Finding] MS (Multiple Sclerosis) 192928003 Multiple Sclerosis 1024685 Multiple Sclerosis 24700007 C0026769 C4282 N0000002052 M0014197 Sclerosis, Disseminated An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) D009103 Demyelinating Autoimmune Diseases, CNS [Disease/Finding]