Metabolism, Inborn Errors [Disease/Finding] Porphyrias [Disease/Finding] D011164 Porphyrias Porphyria Porphyrias 418470004 C5106 29094004 C0032708 1022410 M0017334 A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues. N0000002464 371628009 Skin Diseases, Metabolic [Disease/Finding]