Inflammation [Disease/Finding] Shock [Disease/Finding] Systemic Inflammatory Response Syndrome [Disease/Finding] C0242966 N0000003848 238149007 M0028081 A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS. 1023779 Systemic Inflammatory Response Syndrome D018746 Systemic Inflammatory Response Syndrome 238150007 Inflammatory Response Syndrome, Systemic C7874 Sepsis Syndrome