Didanosine [Chemical/Ingredient] D016049 C22566 C0012133 Didanosine 3364 Didanosine N0000006111 2',3'-Dideoxyinosine Dideoxyinosine Inosine, 2',3'-dideoxy- A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite. M0024535 ddI (Antiviral) Didanosine Dideoxynucleosides [Chemical/Ingredient] Inosine [Chemical/Ingredient]