CI_with has_Ingredient has_MoA has_PE may_treat drug associated with AE in adult drug associated with AE in pediatric used to treat disease Sodium Channel Interactions [MoA] Bipolar Disorder [Disease/Finding] Drug Hypersensitivity [Disease/Finding] Epilepsies, Partial [Disease/Finding] Epilepsy, Tonic-Clonic [Disease/Finding] Pain [Disease/Finding] Spasms, Infantile [Disease/Finding] topiramate [Chemical/Ingredient] Decreased Glutamate Activity [PE] Increased GABA Activity [PE] T [Preparations] TOPIRAMATE http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020505s042,020844s036lbl.pdf <VANDF_Record>50.416^3693^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3693</VA_IEN> N0000148493 38404 Active 4021026 C0076829 TOPIRAMATE <VANDF_Record>50.6^3412^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3412</VA_IEN> C21010 Ingredient topiramate 0H73WJJ391 epilepsy migraine flushing AE dysgeusia AE fever AE infection AE somnolence AE paresthesia AE anorexia AE weight loss AE memory impairment AE cognitive disturbance AE psychomotor retardation AE mood disorder AE