secondary progressive multiple sclerosis 2013-11-07T11:22:49Z A multiple sclerosis that is characterised by a worsening of disability, rather than by relapses followed by recovery, which progressively worsens until a steady progression of disability replaces the cycles of attacks. DOID:0050783 MESH:D020528 SNOMEDCT_US_2016_03_01:425500002 SPMS Secondary-progressive MS UMLS_CUI:C0751965 disease_ontology lschriml multiple sclerosis