occurs in has participant quality has disease treated with drug INTERFERON ALFA-2A ZALCITABINE TOPOTECAN ROPINIROLE TIPRANAVIR FLUCYTOSINE INDOMETHACIN AMIODARONE HYDROCHLORIDE CYTARABINE CYCLOSPORINE RIBAVIRIN LISINOPRIL MITOXANTRONE HYDROCHLORIDE RAMIPRIL BETAXOLOL CLOMIPRAMINE DOXORUBICIN FLECAINIDE METHOTREXATE FLUDARABINE PHOSPHATE CLADRIBINE AMLODIPINE SOTALOL DOCETAXEL TOLCAPONE CAPECITABINE EFAVIRENZ EXEMESTANE BEXAROTENE PEGINTERFERON ALFA-2B IMATINIB OXALIPLATIN ENFUVIRTIDE EMTRICITABINE PEMETREXED ERLOTINIB SORAFENIB LENALIDOMIDE NELARABINE VIGABATRIN TELBIVUDINE IXABEPILONE NILOTINIB HISTRELIN CABAZITAXEL IPILIMUMAB VEMURAFENIB CARFILZOMIB mature T-cell and NK-cell lymphoma estrogen-receptor positive breast cancer EAST syndrome heart conduction disease prostate cancer chronic lymphocytic leukemia hypertension obsessive-compulsive disorder cryptococcosis lymphocytic choriomeningitis Parkinson's disease breast cancer benign eccrine breast spiradenoma cancer pancreatic cancer hepatitis C melanoma hepatitis B colon cancer ovarian cancer hairy cell leukemia dermatofibrosarcoma protuberans non-small cell lung carcinoma aggressive systemic mastocytosis myelodysplastic/myeloproliferative neoplasm human immunodeficiency virus infectious disease acute T cell leukemia hepatocellular carcinoma rheumatoid arthritis chronic myeloid leukemia psoriasis gastrointestinal stromal tumor colorectal cancer multiple myeloma Elderly Child Adult Adolescent fatigue AE 10016256 10024264 NCIt: C3036; NCIt: C78416 lethargy is sometimes reported as an extreme fatigue: http://the-difference-between.com/lethargy/fatigue they are sometimes regarded as synonyms: https://www.nlm.nih.gov/medlineplus/ency/article/003088.htm CTCAE: E11098 (fatigue); CTCAE: E12709 (lethargy) WEB: http://en.wikipedia.org/wiki/Fatigue_%28medical%29 HPO: HP_0003388 a behavior and neurological AE that has an outcome of fatigue, which is a state of awareness describing a range of afflictions, usually associated with physical and/or mental weakness, though varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles. Physical fatigue is the inability to continue functioning at the level of one's normal abilities. SS, YH, MW lethargy AE SIDER: C0015672 behavioral and neurological AE AE severity G1 AE severity G2 AE severity G3