sulfamate ester cyclic ketal ketohexose derivative topiramate 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate 38404 A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. C12H21NO8S CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 CHEBI:63631 CHEBI:9633 ChemIDplus:97240-79-4 CiteXplore:22233396 CiteXplore:22249827 DrugBank:DB00273 InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N KEGG COMPOUND:97240-79-4 KEGG COMPOUND:C07502 KEGG DRUG:D00537 McN-4853 Patent:US4513006 RWJ-17021 Reaxys:5988957 TPM Topamax Topiramate Wikipedia:Topiramate tipiramate tipiramato topiramate topiramato topiramatum