has role has_role has role gene as virulence factor in pathogen gene mutant attenuated in host cell gene mutant attenuated in host has role has_role has role macrophage macrophage 巨噬细胞 Brucella abortus 2308 Brucella melitensis biovar Abortus 2308 Homo sapiens Homo sapiens 人类 protein-coding gene of Brucella melitensis biovar Abortus 2308 glnA 20140405 359391 3788725 BAB1_1023 Bin Zhao, Oliver He I NCBI-supplied PMID: 16299333 WEB: http://www.ncbi.nlm.nih.gov/gene glutamine synthetase protein-coding 1714 MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis glnA gene is required for intracellular multiplication in human macrophage THP-1 cells [PMID:12438693]. virulence factor gene role