part of part_of part of part_of bounding layer of bounding layer of continuous_with continuous with tendon skeletal muscle tissue mesoderm-derived structure dense irregular connective tissue epimysium Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. FMA:9726 NCIT:C32527 The Epimysium also protects muscles from friction against other muscles and bones UBERON:0011899 UMLS:C0504096 epimysia fascia of muscle organ uberon skeletal muscle organ