regulator role role of Institutional Review Board Animal protocol review board Internal Review Board Person:Helen Parkinson role of Institutional Review Board the role of a organization that is realized by members reviewing study designs for their agreement with regulations An institutional review board/independent ethics committee (IRB/IEC) (also known as ethical review board) is a group that has been formally designated to approve, monitor, and review biomedical and behavioral research involving humans with the alleged aim to protect the rights and welfare of the subjects. Wikipedia March 2008 CDISC definition: institutional review board; independent ethics committee (IEC). An independent body (a review board or a committee, institutional, regional, national, or supranational) constituted of medical/scientific professionals and non-scientific members, whose responsibility it is to ensure the protection of the rights, safety and well-being of human subjects involved in a trial. OBI, CDISC Person:Jennifer Fostel metadata complete