loess global transformation two-channel A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay. Elisabetta Manduchi Loess global normalization applied to data from a two-channel expression microarray assay, where the curve is obtained using all reporters. The goal is to remove intensity-dependent biases. OTHER: Editor's generalization based on MGED Ontology term loess global transformation two-channel loess global transformation ready for release