lung disorder respiratory failure NCIT:C26872 UMLS:C1145670 NCIT:C27043 MESH:D012131 DOID:11162 http://purl.obolibrary.org/obo/mondo/releases/2024-01-03/mondo.owl respiratory failure SCTID:39871006 respiratory insufficiency/failure MONDO:i2s ICD9:518.81 acute and chronic respiratory failure MONDO:0021113 ICD9:518.83 MONDO:equivalentTo failure, respiratory DOID:11162 acute-on-chronic respiratory failure ICD9CM:518.84 The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. NCIT:C26872 acute respiratory failure chronic respiratory failure