has participant quality fatigue AE NCIt: C3036 MedDRA: 10016256 (fatigue); MedDRA: 10024264 (lethargy) lethargy AE HPO: HP_0003388 SIDER: C0015672 WEB: http://en.wikipedia.org/wiki/Fatigue_%28medical%29 CTCAE: E11098 SS, YH a behavior and neurological AE that has an outcome of fatigue, which is a state of awareness describing a range of afflictions, usually associated with physical and/or mental weakness, though varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles. Physical fatigue is the inability to continue functioning at the level of one's normal abilities. behavioral and neurological AE AE severity G1 AE severity G2