part of part of develops_from contributes to morphology of immediate transformation of brain forebrain AAO:0010147 BAMS:FB BAMS:Forebrain BTO:0000478 CALOHA:TS-0380 DHBA:10156 DMBA:15566 EFO:0000909 EHDAA2:0000556 EHDAA:3470 EMAPA:16895 FB FMA:61992 In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG] MA:0000170 MAT:0000105 MESH:D016548 MIAA:0000105 Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO] TAO:0000109 The most anterior region the brain including both the telencephalon and diencephalon. The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO] UBERON:0001890 UMLS:C0085140 VHOG:0000383 XAO:0000011 ZFA:0000109 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=27 prosencephalic prosencephalon relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO] uberon regional part of brain anterior neural tube future forebrain