has characteristic chronic pain generalized pain chronic widespread pain 2025-06-23T17:11:58Z Chronic widespread pain (CWP) is associated with significant emotional distress (anxiety, anger/frustration or depressed mood) or functional disability (interference in daily life activities and reduced participation in social roles). CWP is multifactorial: biological, psychological and social factors contribute to the pain syndrome. The diagnosis is appropriate when the pain is not directly attributable to a nociceptive process in these regions and there are features consistent with nociplastic pain and identified psychological and social contributors. Chronic pain that is diffuse and experienced in body regions and in at least 3 or more body quadrants (as defined by upper-lower/left-right side of the body) and axial skeleton (neck, back, chest, and abdomen). Additional criteria to consider: - Include quantrants/regions of body in the definition. - E.g., >= 3 quadrants & axial - >= 4 body regions - Use the notion of functional region instead of regions divided by joints. define as chronic & multi-localized. chronic widespread pain (PAIN) distributed Bill Duncan