develops from
develops from
capable of
capable of
professional antigen presenting cell
phagocyte
macrophage
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.
histiocyte
FMA:63261
BTO:0000801
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
MESH:D008264
CALOHA:TS-0587
FMA:83585
monocyte
myeloid leukocyte
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
phagocytosis
pseudopodium organization