has part realizes has specified input has specified output achieves_planned_objective characteristic of role of has role function methyl group deoxyribonucleotide chromatin evaluant role chromatin immunoprecipitation analyte role DNA methylation profiling assay MeDIP-seq assay url:https://en.wikipedia.org/wiki/Methylated_DNA_immunoprecipitation Philippe Rocca-Serra PMID: 18612301. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Gr�_f S, Johnson N, Herrero J, Tomazou EM, Thorne NP, B�_ckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavar�� S, Beck S. Nat Biotechnol. 2008 Jul;26(7):779-85. A DNA methylation profiling assay that identifies methylated sites in genomic DNA and determines the methylation pattern that affect gene transcription using immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods. MeDIP-seq assay Methylated DNA immunoprecipitation sequencing assay library preparation sequence data DNA extract epigenetic modification identification objective ChIP assay detection technique DNA sequencer sequencing assay metadata complete