needle biopsy core needle biopsy Chris Stoeckert, Helena Ellis, Jie Zheng NCI BBRB CNB https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/ core needle biopsy A core needle biopsy can remove more tissue than a fine needle biopsy, and therefore can provide more information about the cells and tissue removed. A biopsy that uses a hollow tube to collect a core of tissue. ready for release