sequence data reference gene sequence stop site reference gene sequence stop site Emma Griffiths The position of the last nucelotide in a reference sequence (sequence being used for comparison). reference gene stop subject gene stop site When a new genome is sequenced, the termination sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The last nucelotide of a gene sequence used for comparison is the reference gene sequence stop site. Emma Griffiths metadata complete