Hi-C assay capture Hi-C assay capture Hi-C assay https://github.com/obi-ontology/obi/issues/1251 PMID:29979818 cHi-C Bonita Lam PMID:29979818 Chromosome conformation capture (3C), coupled with next-generation sequencing (Hi-C), provides a means for deciphering not only the principles underlying genome folding and architecture, but more broadly, the role 3D chromatin structure plays in gene regulation and the replication and repair of DNA. A Hi-C assay in which a selection step is performed on ligated fragments in order to enrich for ligation products containing specific regions of interest. metadata complete