has characterizing marker set pvalb GABAergic cortical interneuron chandelier pvalb GABAergic cortical interneuron The marker set GPR149, CA8 can identify the Human cell type chandelier pvalb GABAergic cortical interneuron in the neocortex with a confidence of 0.799748111 (NS-Forest FBeta value). A transcriptomically distinct pvalb GABAergic cortical interneuron that is recognizable by the straight terminal axonal 'cartridges' of vertically oriented strings of synaptic boutons. Chandelier PV cells' boutons target exclusively the axon initial segment (AIS) of pyramidal cells, with a single cell innervating hundreds of pyramidal cells in a clustered manner. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Chandelier. chandelier PV interneuron ILX:0107356 In mice, Chandelier PV cells have soma found in in upper L2/3, with some in deep L5 and exhibit fast-spiking but lower firing rate compared to basket cells, and have practically absent hyperpolarization sag. Chandelier PV chandelier cell Homo sapiens