in taxon has primary output L-histidine zwitterion L-histidine biosynthetic process histidine biosynthesis biological_process histidine anabolism MetaCyc:HISTSYN-PWY The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. histidine biosynthetic process histidine synthesis GO:0000105 histidine formation L-histidine metabolic process biosynthetic process aromatic amino acid family biosynthetic process L-amino acid biosynthetic process proteinogenic amino acid biosynthetic process Vertebrata <vertebrates>