in taxon capable of capable of insulin receptor activity insulin receptor complex A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. cellular_component GO:0005899 protein-containing complex plasma membrane signaling receptor complex protein kinase complex Eumetazoa