Cluster RNAseq 001-088 - CS202002013_122 RNAseq 058-088 - CS202002013_179 Glutamatergic Neuronal: Glutamatergic RNAseq 058-088 Excitatory neurons n63 Zizhen Yao Glutamatergic is: Neurons that use glutamate as a neurotransmitter and exert an excitatory post-synaptic effect. The minimal set of markers required to distinguish this cell class from other cell classes in the primary motor cortex is Sv2b and Arpp21 (F-beta = 0.988), based on the NS Forest method of marker gene selection. Glutamatergic cells represent 71.92% of all cells collected in the snRNA-seq 10X v3 B dataset. Glutamatergic cells have an average of 5113 genes detected, which is 832 more than the average for allcells (4281). The average normalized cortical depth of Glutamatergic cells is 0.527, compared to an average of 0.539 for all cells. Glutamatergic cells have an average firing rate of 26.59 Hz, compared to 56.42 Hz for all neurons recorded. Other distinguishing features include an input resistance of 156.52 MOhms (227.12 MOhms in all neurons), and upstroke:downstroke ratio of 4.03 (2.62 for all neurons). The most distinguishing morpholgical features of Glutamatergic, as determined by reconstructions from Patch-seq data, are normalized cortical depth (0.54 vs. 0.46 average for all neurons), dendrite total length (4488.4 vs. 3182.34 microns for all neurons), and stems (7.25 vs. 6.4 for all neurons). Class PMID:34616066 CS202002013_179 {"cell_set_preferred_alias": "Glutamatergic", "original_label": "n63", "cell_set_label": "RNAseq 058-088", "cell_set_accession": "CS202002013_179", "cell_set_aligned_alias": "Neuronal: Glutamatergic", "cell_set_additional_aliases": "", "cell_set_alias_assignee": "Zizhen Yao", "cell_set_alias_citation": "PMID:34616066", "cell_set_structure": "primary motor cortex", "cell_set_ontology_tag": "UBERON:0001384", "species": "Mouse", "modality": "RNAseq", "taxonomy_id": "CCN202002013", "taxonomy_description": "Mouse MOp BICCN taxonomy using multiple RNA-Seq datasets ", "child_cell_set_accessions": "CS202002013_58|CS202002013_59|CS202002013_60|CS202002013_61|CS202002013_62|CS202002013_63|CS202002013_64|CS202002013_65|CS202002013_66|CS202002013_67|CS202002013_68|CS202002013_69|CS202002013_70|CS202002013_71|CS202002013_72|CS202002013_73|CS202002013_74|CS202002013_75|CS202002013_76|CS202002013_77|CS202002013_78|CS202002013_79|CS202002013_80|CS202002013_81|CS202002013_82|CS202002013_83|CS202002013_84|CS202002013_85|CS202002013_86|CS202002013_87|CS202002013_88", "cell_type_card": "Class", "cell_set_color": "#00ADEE"} Neuronal: Glutamatergic Glutamatergic Neuronal: Glutamatergic