exemplar data of Cluster L6 IT primary motor cortex glutamatergic neuron (Mmus) RNAseq 061-068 - CS202002013_186 RNAseq 067-068 - CS202002013_192 L6 IT L6 IT {"cell_set_preferred_alias": "L6 IT", "original_label": "n76", "cell_set_label": "RNAseq 067-068", "cell_set_accession": "CS202002013_192", "cell_set_aligned_alias": "L6 IT", "cell_set_additional_aliases": "", "cell_set_alias_assignee": "Zizhen Yao", "cell_set_alias_citation": "PMID:34616066", "cell_set_structure": "primary motor cortex", "cell_set_ontology_tag": "UBERON:0001384", "species": "Mouse", "modality": "RNAseq", "taxonomy_id": "CCN202002013", "taxonomy_description": "Mouse MOp BICCN taxonomy using multiple RNA-Seq datasets ", "child_cell_set_accessions": "CS202002013_67|CS202002013_68", "cell_type_card": "Subclass", "cell_set_color": "#A19922"} PMID:34616066 Zizhen Yao n76 CS202002013_192 L6 IT is: Layer 6 intratelencephalic-projecting. In Mouse primary motor cortex (CCN202002013), L6 IT has 2 child types: L6 IT_1 and L6 IT_2. The minimal set of markers required to distinguish this cell type from other cell types in the primary motor cortex is Bmpr1b and Il1rapl2 and Sulf1 (F-beta = 0.8), based on the NS Forest method of marker gene selection. L6 IT cells represent 6.01% of all Glutamatergic cells collected in the snRNA-seq 10X v3 B dataset. L6 IT cells have an average of 5205 genes detected, which is 92 more than the average for all Glutamatergic cells (5113). The average normalized cortical depth of L6 IT cells is 0.831, compared to an average of 0.527 for all Glutamatergic cells. L6 IT cells have an average firing rate of 35.14 Hz, compared to 26.59 Hz for all Glutamatergic cells recorded. Other distinguishing features include an input resistance of 185.91 MOhms (156.52 MOhms in all Glutamatergic cells), and upstroke:downstroke ratio of 4.38 (4.03 for all Glutamatergic cells). The most distinguishing morpholgical features of L6 IT, as determined by reconstructions from Patch-seq data, are normalized cortical depth (0.81 vs. 0.54 average for all Glutamatergic cells), dendrite total length (3273.05 vs. 4488.4 microns for all Glutamatergic cells), and stems (6.11 vs. 7.25 for all Glutamatergic cells). L6 IT Subclass L6 IT RNAseq 067-068