exemplar data of Cluster L5 ET primary motor cortex glutamatergic neuron (Mmus) RNAseq 058-073 - CS202002013_181 RNAseq 070-073 - CS202002013_193 Subcerebral projection neurons (SCPN) Subclass Pyramidal tract-like (PT-l) Pyramidal tract (PT) neurons Burst-firing layer 5 neurons L5 ET L5 ET is: Layer 5 extratelencephalic-projecting; also known as CF (corticofugal), PT (pyramidal tract), or SC (subcortical). In Mouse primary motor cortex (CCN202002013), L5 ET has 4 child types: L5 ET_1, L5 ET_2, L5 ET_3 and L5 ET_4. The minimal set of markers required to distinguish this cell type from other cell types in the primary motor cortex is Gm2164 and Npr3 (F-beta = 0.888), based on the NS Forest method of marker gene selection. L5 ET cells represent 2.81% of all Glutamatergic cells collected in the snRNA-seq 10X v3 B dataset. L5 ET cells have an average of 6580 genes detected, which is 1467 more than the average for all Glutamatergic cells (5113). The average normalized cortical depth of L5 ET cells is 0.619, compared to an average of 0.527 for all Glutamatergic cells. L5 ET cells have an average firing rate of 30.92 Hz, compared to 26.59 Hz for all Glutamatergic cells recorded. Other distinguishing features include an input resistance of 88.63 MOhms (156.52 MOhms in all Glutamatergic cells), and upstroke:downstroke ratio of 3.54 (4.03 for all Glutamatergic cells). The most distinguishing morpholgical features of L5 ET, as determined by reconstructions from Patch-seq data, are normalized cortical depth (0.48 vs. 0.54 average for all Glutamatergic cells), dendrite total length (7991.53 vs. 4488.4 microns for all Glutamatergic cells), and stems (8.56 vs. 7.25 for all Glutamatergic cells). L5 ET RNAseq 070-073 L5 ET {"cell_set_preferred_alias": "L5 ET", "original_label": "n77", "cell_set_label": "RNAseq 070-073", "cell_set_accession": "CS202002013_193", "cell_set_aligned_alias": "L5 ET", "cell_set_additional_aliases": "", "cell_set_alias_assignee": "Zizhen Yao", "cell_set_alias_citation": "PMID:34616066", "cell_set_structure": "primary motor cortex", "cell_set_ontology_tag": "UBERON:0001384", "species": "Mouse", "modality": "RNAseq", "taxonomy_id": "CCN202002013", "taxonomy_description": "Mouse MOp BICCN taxonomy using multiple RNA-Seq datasets ", "child_cell_set_accessions": "CS202002013_70|CS202002013_71|CS202002013_72|CS202002013_73", "cell_type_card": "Subclass", "cell_set_color": "#0D5B78"} PMID:34616066 Thick-tufted layer 5 pyramidal neurons Thick-tufted layer 5 neurons (TTL5) L5 ET CS202002013_193 L5b neurons n77 Zizhen Yao RNAseq 070-088 - CS202002013_234