D-mannitol E 421 E421 D-mannitol mannitol (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol Mannitol Mannitol (2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol The <small>D</small>-enantiomer of mannitol. D-(-)-Mannitol D-Mannitol Osmitrol manna sugar mannitol D-mannitol (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol dulcite mannite E-421 D-Mannitol compatible osmolytes metabolite mannitol antiglaucoma drug osmotic diuretic sweetening agent allergen hapten Escherichia coli metabolite food anticaking agent food stabiliser food humectant food thickening agent food bulking agent