glycol butane-1,4-diol 1,4-butylene glycol tetramethylene 1,4-diol HOCH2CH2CH2CH2OH 1,4-dihydroxybutane A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16°C) with a high boiling point (230°C), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). 1,4-tetramethylene glycol 1,4-BUTANEDIOL 1,4-BD HO(CH2)4OH tetramethylene glycol butane-1,4-diol butane-1,4-diol protic solvent prodrug neurotoxin butanediol