has role 4-amino-1,2-oxazolidin-3-one metabolite organonitrogen heterocyclic antibiotic organooxygen heterocyclic antibiotic antitubercular agent antimetabolite D-cycloserine D-4-amino-3-isoxazolidinone A 4-amino-1,2-oxazolidin-3-one that has <i>R</i> configuration. It is an antibiotic produced by <em>Streptomyces garyphalus</em> or <em>S. orchidaceus</em> and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of <small>D</small>-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of <small>L</small>-alanine racemase (which forms <small>D</small>-alanine from <small>L</small>-alanine) and <small>D</small>-alanine—<small>D</small>-alanine ligase (which incorporates <small>D</small>-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis). chebi_ontology PA-94 Ro-1-9213 PA 94 cyclo-D-serine CHEBI:40009 D-Cycloserine (R)-4-AMINO-ISOXAZOLIDIN-3-ONE orientomycin (+)-4-amino-3-isoxazolidinone alpha-Cycloserine D-4-amino-3-isoxazolidone (+)-cycloserine D-(+)-cycloserine DCS CHEBI:4030 NMDA receptor agonist D-cycloserine zwitterion L-cycloserine D-cycloserine(1+)