has part has part has_part has role antibacterial drug dextrofloxacin EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor topoisomerase IV inhibitor DNA synthesis inhibitor racemate levofloxacin ofloxacin DL 8280 chebi_ontology rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid OFLX HOE-280 CHEBI:7731 (+-)-ofloxacin racemic ofloxacin HOE 280 ORF 18489 (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid CHEBI:100146 DL-8280 A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. rac-ofloxacin quinolone antibiotic fluoroquinolone antibiotic