part_of part of part of has part has part has_part capable of has characterizing marker set NS forest marker set of pulmonary neuroendocrine cell (Human lung). neuronal receptor cell sensory epithelial cell neuroendocrine cell chemoreceptor cell serotonin secreting cell pulmonary neuroendocrine cell lung neuroendocrine cell The marker set CHGA, GRP can identify the Human cell type pulmonary neuroendocrine cell in the lung with a confidence of 0.94 (NS-Forest FBeta value). A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. lung secretory cell dense core granule detection of hypoxia lung