chromatin remodeling regulation of gene expression epigenetic regulation of gene expression regulation of gene expression, epigenetic GO:0040029 Reactome:R-HSA-8986944 A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal. biological_process Reactome:R-HSA-212165