part_of part of part of has part has part has_part develops from contributes to morphology of heart CALOHA:TS-0445 GAID:174 chambered heart vertebrate heart VHOG:0000276 UBERON:0000948 EHDAA:420 MAT:0000036 MA:0000072 BILA:0000020 EHDAA2:0000738 MIAA:0000036 A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. NCIT:C12727 Wikipedia:Heart EV:0100018 galen:Heart Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 TAO:0000114 SCTID:302509004 EMAPA:16105 BTO:0000562 AAO:0010210 FMA:7088 XAO:0000064 cardium MESH:D006321 EFO:0000815 ZFA:0000114 mesoderm-derived structure heart tube cardiac chamber cardiovascular system thoracic segment organ primary circulatory organ structure with developmental contribution from neural crest heart plus pericardium