microtubule cytoskeleton organization spindle organization spindle organization and biogenesis GO:0043146 GO:0007051 spindle organisation spindle stabilization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. biological_process cell cycle process