negatively regulates negatively regulates biological_process transferase activity negative regulation of catalytic activity regulation of transferase activity negative regulation of transferase activity downregulation of transferase activity biological_process transferase inhibitor down regulation of transferase activity inhibition of transferase activity This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. GO:0051348 Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. down-regulation of transferase activity